Over time, your skin can develop problems like acne, scars, wrinkles, and discolouration. Figuring out a skincare routine that suits you can take time. However, one significant improvement in skincare is mesotherapy and microneedling. These treatments are suitable for issues like scarring, stretch marks, and other common skin problems with aging. Even though they are alike, they have a few differences.

This article will explain the distinctions between Mesotherapy and microneedling to help you choose the best treatment for your needs.

What is Mesotherapy?

Mesotherapy is a non-surgical treatment that involves using a single, excellent needle to reach the deeper layers of the skin. This tiny needle is designed to penetrate the dermis and go into the subcutaneous tissue below.

During the procedure, a mixture of vitamins, minerals, amino acids, and plant extracts is injected directly into the deeper skin tissue where it’s most needed. This method is more effective than surface treatments because it can provide essential hydration and nourishment to skin cells, supporting their health and recovery.

What is the Purpose of Mesotherapy?

Mesotherapy is a versatile treatment for a variety of skin issues, including:

  • Fine lines and wrinkles.
  • Hyperpigmentation
  • Dehydrated and lackluster skin.
  • Loose skin and localized fat

Its effectiveness originates from its ability to address problems in the skin’s middle layers, making it an excellent treatment for cellulite, saggy skin, and other concerns. Notably, it is a good choice for people with body issues because it can improve the appearance of specific regions.

Mesotherapy works by injecting a fluid that breaks down fat in particular areas. Clients can use Mesotherapy to remove fat in areas that would otherwise be impossible to treat without surgery.

What is Microneedling?

Microneedling, like Mesotherapy, is a non-surgical treatment in which needles enter the dermis. However, there are several significant differences: Microneedling involves using a skin-needling pen to produce a wound in the skin by penetrating the dermis with several ultrafine needles at once.

This procedure increases the skin’s healing response, resulting in the production of new collagen and elastin. When topical products are applied to the skin before treatment, producing these micro-holes in the dermis improves product absorption into the skin cells, maximizing treatment results.

What is the Purpose of Microneedling?

Microneedling is a highly successful treatment for several skin disorders, particularly those affecting the face and neck:

  • Relieve acne surgical scarring,
  • hyperpigmentation,
  • hair loss,
  • wrinkles,
  • texture concerns.

Microneedling is mainly used for skin restoration because it increases more profound cell regeneration, encouraging new skin cell formation. Microneedling treats acne scars on the face, wrinkles around the eyes and neck, and surgical scars on the belly. Because the needles cause the skin’s wound reaction, microneedling is ideal for treating age-related symptoms.

As a result, it stimulates the release of healing properties such as new collagen and elastin.

Difference Between Mesotherapy and Microneedling – Which One Is Best?

It’s all about your desired results when deciding between microneedling and mesotherapy for aesthetic treatment.

To Address the Indications of Ageing

Fine lines and wrinkles are two of the most common and visible signs of aging skin. While Mesotherapy can help your skin cells stay healthy and treat very tiny superficial wrinkles, microneedling is more successful at reducing the appearance of fine lines and wrinkles. The needle movement stimulates collagen and elastin production, which helps smooth out face creases and wrinkles while leaving your skin radiant.

For Skin Texture Issues

Mesotherapy and microneedling improve skin texture issues like dryness, flakiness, and roughness. Microneedling helps renew and exfoliate skin deeply, replacing old cells with new ones. Mesotherapy, conversely, provides nutrients and hydration to your cells, keeping them healthy for a long time and giving your skin a clear and refreshed look.

You can use these treatments together or try alternatives like dermaplaning or a chemical peel for similar results.

Skin Pigmentation Issues

Mesotherapy may be a better alternative. It is because injection concoctions contain vital elements for long-term healthy skin and ingredients that aid in removing sluggish toxins from skin cells. It can help prevent dark circles beneath the eyes and dark or discolored patches of skin, which can be unwelcome.

Is Microneedling or Mesotherapy More Comfortable?

Mesotherapy is regarded as more comfortable than microneedling, even though it is performed using a pistol. It is done significantly faster, making it more straightforward for patients to tolerate. Furthermore, just one needle penetrates the skin, whereas microneedling uses many needles simultaneously.

A topical anesthetic is typically administered to the skin before the microneedling operation, but this is unnecessary for mesotherapy. It demonstrates the difference in comfort level between the two methods.

Combining Microneedling and Mesotherapy

Microneedling and mesotherapy are two treatments that offer benefits for the skin. They can also be combined for a more advanced approach. This combination works well because microneedling is suitable for delivering serums into the deeper layers of the skin when the channels are still open.

While it may not reach as deep as traditional mesotherapy methods, microneedling can boost communication between skin cells, leading to better restoration beyond the surface.

Mesotherapy solutions have improved from essential hydrating serums to more advanced ones with peptides, antioxidants, and things that can help with pigmentation. Using these advanced serums with microneedling can help with skin problems like pigmentation, dryness, uneven texture, and signs of aging.


Mesotherapy and microneedling make your skin look better, but they work in their ways. Mesotherapy puts vitamins and minerals into your skin to make it fresher, while microneedling uses small needles to cause tiny injuries so your skin can heal. Ask a skincare expert to help you decide which is better for your skin.


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